Gearbox Software a mis en ligne un nouveau patch pour la version PC de Duke Nukem Forever. Celui-ci corrige quelques bugs et permet de porter quatre armes en même temps, de modifier le FOV et il propose des textures un peu plus fines.

- 4-weapon inventory option in single player campaign
- MP Server favorites
- Dedicated server overhaul
- FOV can be modified
- Change VOIP to push-to-talk (bandwidth fix)
- VAC anti-cheat system enabled
- Support for Japanese Steam ID’s for PC release in Japan
- Auto-aim fix
- Blood effects on surfaces behind enemies when shot
- Steam.exe no longer uses an unusually high amount of CPU
- Texture quality improvements
- Fixes to prevent single player and multiplayer save data corruption
- Leaderboard exploit fixed
- AMD Dual-Core Optimizer no longer automatically installed (fixes rare bugs with Intel processors)
- Crash/compatibility fixes and other minor bugs